Post by Radrook Admin on Sept 1, 2020 16:38:18 GMT -5
Neurofibroma of the skin in a person with neurofibromatosis type I
A neurofibroma is a benign nerve-sheath tumor in the peripheral nervous system. In 90% of cases, they are found as stand-alone tumors, while the remainder are found in persons with neurofibromatosis type I (NF1), an autosomal-dominant genetically inherited disease. They can result in a range of symptoms from physical disfiguration and pain to cognitive disability.
Neurofibromas arise from nonmyelinating-type Schwann cells that exhibit biallelic inactivation of the NF1 gene that codes for the protein neurofibromin. This protein is responsible for regulating the RAS-mediated cell growth signaling pathway. In contrast to schwannomas, another type of tumor arising from Schwann cells, neurofibromas incorporate many additional types of cells and structural elements in addition to Schwann cells, making it difficult to identify and understand all the mechanisms through which they originate and develop.
Radrook Admin: Welcome to all the new members and thank you all for joining the forum. For some strange reason, it is only now that I was informed that others had joined. My apologies.
Aug 13, 2023 4:37:21 GMT -5
Radrook Admin: Welcome to the Forum Sanya!
Jun 21, 2023 15:04:34 GMT -5
Radrook Admin: Welcome to the forum Abdul! Thanks for joining!
May 29, 2023 22:40:18 GMT -5
Radrook Admin: Yes, sooner or later this entire website will disappear with everything posted on it for lack of finding someone to take over when I croak. But it won't be because you folks are refusing to respond. That I can guarantee.
Feb 26, 2023 7:10:41 GMT -5
Radrook Admin: That's one reason why I stopped providing long insights into the chess games I play. It's like speaking to the wall.
Feb 26, 2023 7:06:45 GMT -5
Radrook Admin: Funny how I can have approx. 400 people at one point browsing, and not one of them wants to give feedback nor participate in any way manner or form. Not even a simple click with a like.
Feb 26, 2023 7:03:49 GMT -5
Radrook Admin: Funny how these discussion forums were all the rage once until Twitter and YouTube and other such discussion venues came along.
Feb 13, 2023 8:40:52 GMT -5
Radrook Admin: I wish visitors would say something instead of just reading and leaving in silence. Or at the least, at least have the courtesy to rate the material.
Feb 4, 2023 21:26:37 GMT -5
Radrook Admin: Thinking that doctors are beyond criticism no matter what is a cultural trait I do not share.
Feb 3, 2023 12:48:59 GMT -5
Radrook Admin: Reporting physician malpractice might save someone else from getting murdered.
Jan 31, 2023 9:10:52 GMT -5
Radrook Admin: Funny how nobody believes you when you describe physician malpractice until it happens to them-isn't it.
Jan 30, 2023 21:13:57 GMT -5
Radrook Admin: Just restored the History section. Hopefully this one won't disappear like the last one did.
Jan 25, 2023 16:37:13 GMT -5